Re: [AMMRL] a simple 2D TOCSY on a bruker cryoprobe

From: D'Anciaes Almeida Silva, Igor via groups.io <idhbx=missouri.edu_at_groups.io>
Date: Thu, 24 Jul 2025 14:30:53 +0000

Hi Serge,

I'd start checking the peak powers for the nuclei involved at "edprobe".
Maybe the ones at the pulse sequence are higher then what its written there.

Best,

----------------
Dr. Igor d'Anciães Almeida Silva
Research Scientist - NMR Core
University of Missouri-Columbia
32A Chemistry Building
________________________________
> From: main_at_ammrl.groups.io on behalf of serge_lavoie via groups.io
> Sent: Thursday, July 24, 2025 8:58 AM
> To: main_at_ammrl.groups.io <main_at_ammrl.groups.io>
> Subject: [AMMRL] a simple 2D TOCSY on a bruker cryoprobe


Hi all,

I am trying to record a basic 2D TOCSY experiment with our instrument (Bruker
Neo 500 MHz, cryoprobe prodigy BBO). For a reason i dont understand, it fails
after a few dummy scan with this error message: 'EMERGENCY-STOP activated:
Peak power limit exceeded, EmStop activated...'. I have verified that
the probe was correctly tuned and matched. I have checked that all pulse
length and power are set according to the pulse program instruction. Here a
the most important parameter i used:


  * pulprog: dipsi2gpphzs
  * td = 4096 x 256
  * ds = 16, ns = 8
  * d1 = 2 s; d9 = 80 ms
  * sw = 2778 x 2778 Hz; o1p = 3.25 ppm
  * p1 = 10 µs, p6 = 30 µs, p32 = 20 ms
  * pldb1 = -11.92 db; pldb10 = -2.3807 db; spdb29 = 12.26 db

Note that using the same instrument, i successfully recorded 1H, 13C, hsqc,
hmbc, dqf-cosy, even hsqc-tocsy experiments. What is wrong with 2d tocsy?

Serge Lavoie
Université du Québec à Chicoutimi
Saguenay (Québec)




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Received on Thu Jul 24 2025 - 07:48:12 MST

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