[AMMRL] Adding 40/60 D2O/d-sulfuric acid as a lock solvent?

From: Wendy Breyer via groups.io <web216=lehigh.edu_at_groups.io>
Date: Mon, 12 May 2025 13:59:39 -0700

Hello,

A user ran a reaction in a ~40/60 D2O/d-sulfuric acid mixture so that she
could directly analyze her products via NMR.  However, when she used
D2O as the lock solvent, she found her peaks shifted significantly (e.g.
aromatic peaks at 2-3ppm).  We are thinking that we should add the
40/60 D2O/d-sulfuric acid mixture to our Solvents table.  Has anyone
added a similar entry?  What signal values did you use? Or is there
another way around this issue?

Thanks!

Wendy


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Received on Tue May 13 2025 - 03:22:30 MST

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