AMMRL: NMR Scientist position at T2 Biosystems

From: Walter Massefski <massefskiww_at_gmail.com>
Date: Mon, 26 Jan 2015 12:16:30 -0500

T2 Biosystems in Lexington, Massachusetts has an open position for an NMR Scientist; if anyone is interested, have a look at the posting (below, or on the T2 Biosystems website) and send your application to the Careers address at careers_at_t2biosystems.com

I am happy to answer any and all questions at this address, and for those on the East Coast - enjoy the snow!
Walt

massefskiww_at_gmail.com

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NMR Scientist

T2 Biosystems, founded in 2006 by renowned scientists from MIT and Mass General Hospital, is an in vitro diagnostic company that has developed an innovative and proprietary technology platform that offers a rapid, sensitive and simple alternative to existing diagnostic methodologies. We are using our T2 Magnetic Resonance platform, or T2MR, to develop a broad set of applications aimed at reducing mortality rates, improving patient outcomes and reducing the cost of healthcare by helping medical professionals make targeted treatment decisions earlier. T2MR enables rapid detection of pathogens, biomarkers and other abnormalities in a variety of unpurified patient sample types, including whole blood, and can detect cellular targets as limits of detection as low as one colony forming unit per milliliter, or CFU/ml. Our initial development efforts utilizing T2MR target sepsis and hemostasis, which are areas of significant unmet medical need in which existing therapies could be more effective with improved diagnostics. We have completed a pivotal clinical trial for our T2Dx diagnostic instrument, or T2Dx, and T2 Candida panel, or T2Candida, which have the ability to rapidly identify the five clinically relevant species of Candida, a fungal pathogen known to cause sepsis.

On September 22, 2014, T2 Biosystems received market authorization from the U.S. Food and Drug Administration (FDA) for its first two products, the T2Candida® Panel and the T2Dx® Instrument for the direct detection of Candida species in human whole blood specimens from patients with symptoms of, or medical conditions predisposing the patient to, invasive fungal infections. T2Candida and T2Dx, for the first time, provide sensitive detection of specific sepsis-causing pathogens directly from a whole blood specimen in approximately four hours. All other currently FDA-cleared detection systems require cultured blood samples for species-specific identification and take two to five days or more to provide results.

We are seeking a talented and highly motivated individual to join our team as an NMR Scientist. This position will initially report directly to the Chief Scientific Officer.

Responsibilities:
· Develop, evaluate, and optimize NMR signal acquisition and processing methods

· Participate in the development of NMR detection probes, spectrometers, and magnets

· Plan, review analyze, and document data, algorithms and experiments

· Participate in research and development efforts into targeted areas of new applications for T2MR

· Participate on multi-disciplinary project teams in a matrixed product development environment

Skills and Experience:
· Ph.D. in a physical science specializing in magnetic resonance methods, signal processing, and instrumentation

· 3+ years post-graduate experience

· Demonstrated accomplishments in NMR hardware development with application to biological or chemical systems

· Expertise in the use of complex data analysis tools (e.g. MATLAB, JMP) for interpretation of NMR observables

· Established track record for productivity, particularly recent peer-reviewed publications

· Demonstrated expertise in magnetic resonance instrumentation design, fabrication, and testing

· Experience in low-field NMR and the interpretation of relaxometry data

· Experience with low power, portable instrument design

· Experience applying NMR to biological systems

· Have a track record for innovation

· Succeed working in a team-based cross functional organization

· Demonstrate a history of working successfully outside your comfort zone

· Be self-motivated, an excellent communicator and highly analytical

· Have the ability to work in a fast-paced environment and maintain focus on deliverables

T2 Biosystems is an equal opportunity employer. We do not discriminate on the basis of race, color, religion, gender, pregnancy, national origin, age, military service eligibility, veteran status, sexual orientation, marital status, disability, or any other protected class.
Received on Mon Jan 26 2015 - 07:16:36 MST

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