Hi Ken,
A 2D approach would probably work better for most characterization questions.
But if it had to be a 1D, I've two ideas for those interested in tinkering
with it.
1.
Treat it like an incomplete decoupling problem, only apply the reverse strategy,
where making things worse becomes the goal. Lower decoupler power and/or move
the offset away from peaks of interest. Would work better the further apart
the signals are, though it won't be any help for targeting signals in the
middle of each other.
2.
Have you ever used PROHOMODEC? It does a decent job with selective decoupling.
Reconfiguring the decoupler nuclei to P31 instead might work. The trick would
be narrowing the excitation range by changing pw and plw. I'd try updating the
prosol table with a much lower power calibration and see how it behaved, being
careful to stay within probe specs. If successful, it would let you choose any
signal to center the decoupler on, and I'm curious much selective it would be.
Kind regards,
Luke
Luke Fulton, PhD
CHEM BLDG R003
NMR Core Facility Director
Unit 3060
COR2E & Department of Chemistry
55 N Eagleville Road
University of Connecticut
Storrs, CT 06279
email: fko24003_at_uconn.edu
(alias): luke.fulton_at_uconn.edu
mobile: (603) 953-5275
Office: (860) 486-4069
________________________________
> From: main_at_ammrl.groups.io on behalf of Steve Clemens via groups.io
> Sent: Tuesday, November 4, 2025 11:09 AM
> To: main_at_ammrl.groups.io <main_at_ammrl.groups.io>
> Subject: Re: [AMMRL] Proton with Selective 31P Decoupling
Ken,
Not with selectively decoupling a particular 31P nucleus specifically, but
in my experience a 1H-31P HMBC works VERY well. I sometimes observe couplings
up to 5 bonds distant.
hmbcgplpndqf, GPZ1=60, GPZ2=45, GPZ3=57.6, all SMSQ10.100 shape
-=-=-=-=-=-=-=-=-=-=-=-
Groups.io Links: You receive all messages sent to this group.
View/Reply Online (#2971): https://urldefense.com/v3/__https://ammrl.groups=
.io/g/main/message/2971__;!!PvDODwlR4mBZyAb0!XhFJn2R-WFkpmfOC5wwPlUFf7KG4oY=
4eqldHwljPboWSrnZFrYm_dj888RBroIPJp_4KNxfvvWJfSGjlahV2PD15qqvn$
Mute This Topic: https://urldefense.com/v3/__https://groups.io/mt/116100372=
/7559972__;!!PvDODwlR4mBZyAb0!XhFJn2R-WFkpmfOC5wwPlUFf7KG4oY4eqldHwljPboWSr=
nZFrYm_dj888RBroIPJp_4KNxfvvWJfSGjlahV2PC1e-Fqe$
Group Owner: main+owner_at_ammrl.groups.io
-=-=-=-=-=-=-=-=-=-=-=-
Received on Tue Nov 04 2025 - 13:28:43 MST