Good morning Weixing,
We routinely used Wilmad 528s and often Norrell 502-7s at 800 MHz with no
problems. The "caveat" is that we didn't spin anything and especially not
biomolecules - with modern shim systems and 3D shimming you should get good
spectra non-spinning. The marketing for the higher rated tubes is that they
have better concentricity and camber (frankly I think they just make tubes
to the higher specs and downgrade ones to whatever spec they do meet during
QC). Anyway, more perfect tubes are supposed to minimize artifacts when
spinning which get exacerbated at higher field.
I would avoid anything too cheap, and of course make sure the tubes you use
are straight and fit well in the spinner.
Cheers,
Andrew
On Tue, May 19, 2026 at 5:40 PM Zhang, Weixing via groups.io wrote:
> Dear Colleagues,
>
> I would appreciate your input regarding NMR tube selection for high-field
> applications.
>
> In the past, I routinely used Wilmad 535-PP-7-5 tubes on a 600 MHz
> instrument with good results. However, the current pricing of these tubes
> has increased substantially. Both Wilmad and Norell now offer tubes
> specifically marketed for 800 MHz applications, such as the Wilmad
> 541-PP-7-5 and Norell S-5-800-7, but these products come at a significant
> premium. In practice, however, I have not often observed these higher-cost
> tubes being widely used, even on 800 MHz or 1.1 GHz systems.
>
> From your experience, what are the primary risks or limitations associated
> with using lower-specification tubes — for example, tubes nominally rated
> for 300 MHz — on a 600 MHz instrument, particularly for quantitative
> applications such as determining composition and concentration through
> signal integration in different samples?
>
> I would greatly appreciate any guidance regarding acceptable tolerances,
> observed deviations, or practical trade-offs.
>
> Best regards,
>
> Weixing Zhang
>
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Received on Wed May 20 2026 - 05:40:03 MST