Dear Beth,
We had the same issue on a 400 Avance Neo system after upgrading from TS 4.2.0
to TS 4.3.0 Adding ‘rga’ to the topshim command in the automation
solved the issue.
Hope it helps,
Christoph
> Von: main_at_ammrl.groups.io Im Auftrag von Sham, Shing via groups.io
> Gesendet: Saturday, 18 January 2025 00:42
> An: main_at_ammrl.groups.io
> Betreff: Re: [AMMRL] "Topshim Failed: Signal to noise is too low"
Hi Beth,
Also, when CDCl3 is old, it acidifes and becomes DCl. It decreases the CDCl3
lock signal intensity.
I always ask the users the age of the bottle and how it is kept when shimming
is a problem.
Good luck.
Simon
________________________________
> From: main_at_ammrl.groups.io on behalf of Feng Qiu via groups.io
> Sent: Friday, January 17, 2025 4:58:24 PM
> To: main <main_at_ammrl.groups.io
> Subject: Re: [AMMRL] "Topshim Failed: Signal to noise is too low"
Hi Beth,
I would check the 2H tuning and 2H 90 degree pulse.
Thanks,
Feng
On Friday, January 17, 2025 at 02:13:05 PM EST, Beth Moscato via groups.io wrote:
Hi everyone-
We have an AVANCE III (TS 3.7pl5) that’s been sporadically failing
samples saying that the signal to noise is too low. Most of the samples seem
to be marginal quality – usually CDCl3, sometimes with precipitate
or water droplets – but they often manage to successfully shim on
our AV III HD spectrometer, and I’ve noticed a dramatic uptick in
the number of failures recently.
Note that most samples, including most samples in CDCl3, have successfully
run in TS. The TS data I’ve seen from the failed samples show a similar
pattern to those from normal samples (suggesting that the difference is
quantitative and not qualitative).
I’ve done a 3D shim recently, but it hasn’t helped. The lock
phase is set appropriately.
Is there a way to increase the number of scans acquired in TS for specific
solvents? I’m not thrilled with it as a work around, but if it stops
failing the samples, that would be an improvement over the current situation.
Thank you!
Beth Moscato
Temple University
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Received on Tue Jan 21 2025 - 07:29:45 MST