Dear all,
I have a question on whether there is any easy way to assign the absolute configurations of optical isomers. We are trying to get crystals for X-ray now, but if anyone could suggest an EASY way to identify the absolute configuration after chiral HPLC separation, I would greatly appreciate it. Per AMMRL rules, the structure and partial spectrum is posted in this website. The solvent is DMSO, and the spectrum is obtained from a racemic mixture.
http://cop.utmem.edu/pharmacy/pharmsci/faculty/med_chem/wli/weili_question.htm
Any suggestions would be highly appreciated.
Wei Li
Wei Li, Ph.D.
Assistant Professor and Director of NMR Facility
Department of Pharmaceutical Sciences
College of Pharmacy
University of Tennessee Health Science Center
847 Monroe Ave., room 327A
Memphis, TN 38163
901-448-7532 (Phone)
901-448-6828 (FAX)
Received on Thu Sep 14 2006 - 18:08:51 MST