Dear David,
I too have seen these distortions.
Advice given by the Darmstadt Apps. lab. seemed to work for me, namely
maximise your lockphase in the acqi window ( whilst locked on ).
The artifacts are then minimised at the very least, sometimes they go away
completely ! ;-)
Mark Dixon
AstraZeneca R&D Charnwood,
Loughborough, UK.
> ----------
> From: David Grace[SMTP:DG_at_NYCOMED.COM]
> Sent: Wednesday, September 06, 2000 3:31:33 PM
> To: ammrl_at_wwitch.unl.edu
> Subject: Resonance distortions when using wet for solvent suppression
> Auto forwarded by a Rule
>
Hello everyone.
We have been using the wet solvent suppression sequence for suppressing the
water resonance in 1D proton spectra. When we do this on our pfg id probe on
the Varian Inova 500 we observe a distortion on resonances removed from the
suppression point. The distortion is most noticeable on sharp intense
singlets. Such a distorted singlet seems unusually sharp on one side and has
a marked negative spike, whilst the other side is normal or maybe somewhat
broadened. Its like I've applied resolution enhancement to one side of the
resonance and line-broadening to the other side! The effect is present even
using only one transient and no steady state pulses.
Has anyone seen this and if so an explanation? It would also be nice with a
solution as well!
best wishes,
David Grace
Nycomed Amersham
Manger NMR group, Oslo, Norway
voice +47 23185006
fax+47 23186014
Received on Thu Sep 07 2000 - 11:19:23 MST