We have been looking at the proton NMR of several steroids and noticed the
upfield shift of the protons in the A ring upon substitution at the 11
position with an ester. This is supposed to be a classic example of some
ring current effect, pi cloud shielding. Does anyone have an original
reference where this is discussed? Any leads would be helpful.
Thanks.
Dwaine.
ALCON RESEARCH, LTD.
M/S: R-NMR
6201 South Freeway
Fort Worth, Texas 76134-2099
817-551-8003
FAX 817-568-7675
dwaine.thomas_at_alconlabs.com
Received on Wed Feb 27 2002 - 10:51:00 MST