gradient strengths for DOSY experiments

From: Katherine Aubrecht <KAUBRECH_at_holycross.edu>
Date: Mon, 13 Dec 2004 16:19:09 -0500

We have a Varian 400 MHZ Inova instrument with Performa 1 Z axis gradients- the highest gradient strength is 30 Gauss cm-1. I am interested in doing PGSE experiments on aqueous solutions of polymeric micelles to measure their diffusion coefficients. The diffusion coefficients are small * on the order of 10-9 to 10-12 m2 s-1. I would plan to use the Dbppste-convection controlled pulse sequence. In order to get significant attenuation in the signal, I would need to use long delays during the sequence- 0.5 to 1.5 seconds.

At this point, we can not afford an upgrade to higher strength gradients. Are there any opinions on the validity of the experiment I am proposing to do?


thanks

Katherine Aubrecht
Assistant Professor
Department of Chemistry
College of the Holy Cross
kaubrech_at_holycross.edu
508 793 3378
Received on Tue Dec 14 2004 - 08:40:21 MST

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